Metabolic Engineering

Metabolic Engineering in Indian Institute of Technology

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Created by IIT Kharagpur Staff Last updated Thu, 24-Feb-2022 English


Metabolic Engineering free videos and free material uploaded by IIT Kharagpur Staff .

Syllabus / What will i learn?

Week 1:Introduction to Metabolic Engineering, Basic concepts; Scopes and Applications; Metabolism overview _1 (Cellular Transport processes, Fueling Reactions)

Week 2:Cellular Metabolism Overview_2 (Biosynthetic reactions, Polymerization, Growth Energetics); Regulation of Metabolic Pathways

Week 3: Reconstruction of Genome-scale metabolic network 
Week 4:Examples of pathway manipulations by metabolic engineering : Ethanol, Aminoacids, antibiotics, vitamines, biopolymers, etc.

Week 5Examples of pathway manipulations by metabolic engineering : Improvements of cellular properties, Biodegradation, 
Week 6:Metabolic Flux Analysis: Flux Balance Analysis (FBA), Flux Variability Analysis, Flux Map
Week 7:Experimental determination of Metabolic Fluxes: Isotope labeled substrate, Isotope mapping Mapping Matrix, Isotope Distribution Vector
Week 8:Application of metabolic Flux Analysis


Curriculum for this course
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Description

Overview

Metabolic engineering is an emerging field of biotechnology/bioprocess engineering which aims towards purposeful modification of cellular (metabolic, gene regulatory, and signalling) processes/networks to achieve desirable goals such as enhanced production of metabolites including pharmaceuticals, biofuels and biochemicals and other biotechnology products. This course aims to provide fundamental and advanced knowledge in the development of microbial strain for bio production through metabolic engineering.as INTENDED AUDIENCE :B Tech (Biotechnology/Bioengineering); B Sc. (Microbiology, Biotechnology, Botany); M Sc. (Biotechnology / Life Sciences)PREREQUISITES : Basics of Microbiology, Biochemistry, GeneticsINDUSTRIES SUPPORT :None
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Free

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