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Welcome; Introduction and course organization
Chemical bonding and molecular interactions; Lipids and membranes
Structures of amino acids, peptides and proteins
Enzymes and metabolism
Carbohydrates and glycoproteins
Nucleic acids
Replication
Transcription
Chromatin remodeling and splicing
Translation
Cells, the simplest functional units
Genetics 1—Cell division and segregating genetic material
Genetics 2—Rules of inheritance
Genetics 3—Linkage, crossing over
Genetics 4—The power of model organisms in biological discovery
Recombinant DNA, cloning, and editing
Genomes and DNA sequencing
SNPs and human genetics
Cell trafficking and protein localization
Cell signaling 1—Overview
Cell signaling 2—Examples
Neurons, action potential, and optogenetics
Cell cycle and checkpoints
Stem cells, apoptosis, and tissue homeostasis
Cancer 1
Cancer 2
Visualizing life—Dyes and stains
Visualizing life—Fluorescent proteins
Cell imaging techniques
Immunology 1—Diversity, specificity, and B cells
Immunology 2—Memory, T cells, and autoimmunity
Infectious disease, viruses, and bacteria
Bacteria and antibiotic resistance
Viruses and anti-viral resistance
Reproductive cloning and embryonic stem cells
Introductory Biology provides an introduction to fundamental principles of biochemistry, molecular biology, and genetics for understanding the functions of living systems. Taught for the first time in Fall 2013, this course covers examples of the use of chemical biology and twenty-first-century molecular genetics in understanding human health and therapeutic intervention.
The MIT Biology Department Introductory Biology courses 7.012, 7.013, 7.014, 7.015, and 7.016 all cover the same core material, which includes the fundamental principles of biochemistry, genetics, molecular biology, and cell biology. Biological function at the molecular level is particularly emphasized and covers the structure and regulation of genes, as well as the structure and synthesis of proteins, how these molecules are integrated into cells, and how these cells are integrated into multicellular systems and organisms. In addition, each version of the subject has its own distinctive material.
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